Choi-Sledeski, Yong Mi: search on Z-Library

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1

Crystal Structures of Human Factor Xa Complexed with Potent Inhibitors

Maignan, Sébastien, Guilloteau, Jean-Pierre, Pouzieux, Stéphanie, Choi-Sledeski, Yong Mi, Becker, Michael R., Klein, Scott I., Ewing, William R., Pauls, Henry W., Spada, Alfred P., Mikol, Vincent

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 427 KB

english, 2000

2

Molecular Structures of Human Factor Xa Complexed with Ketopiperazine Inhibitors: Preference for a Neutral Group in the S1 Pocket

Maignan, Sébastien, Guilloteau, Jean-Pierre, Choi-Sledeski, Yong Mi, Becker, Michael R., Ewing, William R., Pauls, Henry W., Spada, Alfred P., Mikol, Vincent

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 540 KB

english, 2003

3

Dimerization of β-tryptase inhibitors, does it work for both basic and neutral P1 groups?

Guyan Liang, Yong Mi Choi-Sledeski, Xin Chen, Yong Gong, Eric W. MacMillan, Joseph Tsay, Keith Sides, Jennifer Cairns, Berndt Kulitzscher, David J. Aldous, Isabelle Morize, Henry W. Pauls

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 1.05 MB

english, 2012

4

Synthesis, SAR and in vivo activity of novel thienopyridine sulfonamide pyrrolidinones as factor Xa inhibitors

Michael R. Becker, William R. Ewing, Roderick S. Davis, Henry W. Pauls, Cuong Ly, Aiwen Li, Helen J. Mason, Yong Mi Choi-Sledeski, Alfred P. Spada, Valeria Chu, Karen D. Brown, Dennis J. Colussi, Robe

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 342 KB

english, 1999

5

Design and Structure−Activity Relationships of Potent and Selective Inhibitors of Blood Coagulation Factor Xa

Ewing, William R., Becker, Michael R., Manetta, Vincent E., Davis, Roderick S., Pauls, Henry W., Mason, Helen, Choi-Sledeski, Yong Mi, Green, Daniel, Cha, Don, Spada, Alfred P.

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 413 KB

english, 1999

6

Structure-based design, synthesis, and profiling of a β-tryptase inhibitor with a spiro-piperidineamide scaffold, benzylamine P1 group, and a substituted indole P4 group

Liang, Guyan, Choi-Sledeski, Yong Mi, Poli, Gregory B., Chen, Xin, Minnich, Anne, Wang, Qingping, Tsay, Joseph, Sides, Keith, Vaz, Roy J.

Journal:

Year:

2011

Language:

english

File:

PDF, 280 KB

english, 2011

7

Solid-phase parallel synthesis of azarene pyrrolidinones as factor Xa inhibitors

Yong Gong, Michael Becker, Yong Mi Choi-Sledeski, Roderick S Davis, Joseph M Salvino, Valeria Chu, Karen D Brown, Henry W Pauls

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 147 KB

english, 2000

8

The Practice of Medicinal Chemistry || Designing Prodrugs and Bioprecursors

Choi-Sledeski, Yong Mi

Year:

2015

Language:

english

File:

PDF, 7.22 MB

english, 2015

9

Brain Penetrable Inhibitors of Ceramide Galactosyltransferase for the Treatment of Lysosomal Storage Disorders

Thurairatnam, Sukanthini, Lim, Sungtaek, Barker, Robert H., Choi-Sledeski, Yong Mi, Hirth, Bradford H., Jiang, John, Macor, John E., Makino, Elina, Maniar, Sachin, Musick, Kwon, Pribish, James R., Mun

Journal:

ACS Medicinal Chemistry Letters

Year:

2020

File:

PDF, 298 KB

2020

10

Discovery of an Orally Efficacious Inhibitor of Coagulation Factor Xa Which Incorporates a Neutral P 1 Ligand

Choi-Sledeski, Yong Mi, Kearney, Robert, Poli, Gregory, Pauls, Henry, Gardner, Charles, Gong, Yong, Becker, Michael, Davis, Roderick, Spada, Alfred, Liang, Guyan, Chu, Valeria, Brown, Karen, Collussi,

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 91 KB

english, 2003

11

A β-tryptase inhibitor with a tropanylamide scaffold to improve in vitro stability and to lower hERG channel binding affinity

Guyan Liang, Yong Mi Choi-Sledeski, Patrick Shum, Xin Chen, Gregory B. Poli, Vasant Kumar, Anne Minnich, Qingping Wang, Joseph Tsay, Keith Sides, Jiesheng Kang, Ying Zhang

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 528 KB

english, 2012

12

A conformationally constrained inhibitor with an enhanced potency for β-tryptase and stability against semicarbazide-sensitive amine oxidase (SSAO)

Guyan Liang, Yong Mi Choi-Sledeski, Gregory Poli, Xin Chen, Patrick Shum, Anne Minnich, Qingping Wang, Joseph Tsay, Keith Sides, Jennifer Cairns, Gregory Stoklosa, Thaddeus Nieduzak, Zhicheng Zhao, Ji

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 401 KB

english, 2010

13

Sulfonamidopyrrolidinone Factor Xa Inhibitors: Potency and Selectivity Enhancements via P-1 and P-4 Optimization

Choi-Sledeski, Yong Mi, McGarry, Daniel G., Green, Daniel M., Mason, Helen J., Becker, Michael R., Davis, Roderick S., Ewing, William R., Dankulich, William P., Manetta, Vincent E., Morris, Robert L.,

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 241 KB

english, 1999

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